In this video it is demonstrated that how to convert American pound into kilograms. First of all we will see the equation for converting weight from American pound to kilograms is American pound divided by 2.2. When pound is divided by 2.2 it will give kilogram weight, for example 40 pounds divided by 2.2 will come around 18.2 kilogram. Now if you want to calculate 25 milligram per kilogram dose, then you have to first divide pound by 2.2, like in previous example it comes to 18.2, then you have to multiply it with 25, now you will get correct answer that is 455 milligram per kilogram dose. It is very simple by applying above equation to convert pound into kilogram.